Retatrutide
Price range: £50.00 through £150.00
Synthetic peptide, supplied lyophilised as a reference standard for laboratory research.
- Investigational compound in active clinical development. No marketing authorisation in any territory
- Lot matched certificate of analysis with every order
- Research use only. Not for human or veterinary use
- Research use only Not for human or veterinary use
- Certificate per lot Published against the lot number
- Independently tested RP-HPLC with LC-MS identity
- Restricted sale 18+ qualified researchers only
Certificates of analysis
Every lot is analysed by RP-HPLC with LC-MS identity confirmation. Select a lot to view its full report.
Regulatory status
Read this section before ordering. Retatrutide is an investigational medicinal product in active clinical development. It holds no marketing authorisation from the Medicines and Healthcare products Regulatory Agency in the United Kingdom, from the Food and Drug Administration in the United States, or from the European Medicines Agency. It is not approved in any territory for any indication.
Under the Human Medicines Regulations 2012 an investigational compound of this kind may not lawfully be supplied for use in humans outside a clinical trial that has been authorised by the MHRA and given a favourable opinion by a research ethics committee. The MHRA has stated its position on compounds in this class repeatedly and has taken enforcement action in this area, including safety alerts and work with police and trading standards authorities.
This listing is an analytical reference standard for laboratory research and nothing else. NH Peptides does not supply it for use in humans or animals, does not supply it to individuals for personal use, and provides no information on this page relating to any such use. If that is what you are looking for, this is not the correct supplier and no correspondence will change that.
What is retatrutide?
Retatrutide is a synthetic peptide. In the published pharmacology literature it is characterised as an agonist at three receptors: the glucose dependent insulinotropic polypeptide receptor, the glucagon like peptide 1 receptor and the glucagon receptor. It carries the development code LY3437943 and originates from Eli Lilly.
The designation is a development code rather than an international non-proprietary name, which is normal for a compound that has not completed regulatory review.
Where the evidence stands
The compound is in phase 3 clinical development. Clinical trial data are the property of the sponsor and are published in the peer reviewed literature and on trial registries. This page does not summarise those results, discuss any indication under investigation, or restate any endpoint, because doing so would describe a use that this material is not supplied for.
Investigators should work from the primary literature and the trial registry record. A large volume of secondary commentary about this compound is in circulation and much of it is unreliable.
Specification figures for retatrutide
The sequence, molecular formula and molecular weight for the lot supplied are stated on its certificate of analysis. Published figures for research compounds are not always consistent between sources, so this page defers to the certificate rather than restating a value that may not match the material in the vial.
Working with material of this class
This is a long chain modified peptide and its analytical profile is correspondingly more complex than the short sequences in the catalogue. Related substance peaks are more numerous, and a purity figure alone tells you less about a lot than it does for a tripeptide. Read the chromatogram on the certificate rather than the headline figure.
Material supplied for research is not manufactured to the standards that apply to a licensed medicinal product, and no comparison should be drawn between the two.
Analysis and certification
Each lot of retatrutide is analysed by an independent laboratory using RP-HPLC with LC-MS identity confirmation before it is released for sale. The certificate of analysis is published against the lot number rather than the product page, so the document you read is the document for the vial you receive.
Research use only
NH Peptides supplies retatrutide as an analytical reference standard for laboratory research. It is not supplied for any use in humans or animals, and no information on this page describes or implies any such use. Sale is restricted to qualified researchers and to purchasers acting on behalf of a research institution, laboratory or business.
| Choose Size | 10mg, 20mg, 30mg, 40mg, 60mg |
|---|
| Compound | Retatrutide |
|---|---|
| Development code | LY3437943 |
| Class | Synthetic modified peptide |
| Regulatory status | Investigational. No marketing authorisation in any territory |
| Sequence | Stated on the certificate of analysis |
| CAS number | Stated on the certificate of analysis |
| Molecular formula | Stated on the certificate of analysis |
| Molecular weight | Stated on the certificate of analysis |
| Appearance | White to off white lyophilised powder |
| Purity specification | ≥99% |
| Identity method | LC-MS |
| Purity method | RP-HPLC |
| Labelled quantity | Per variation, stated on the vial label |
| Intended use | Laboratory research only. Not for human or veterinary use |
How retatrutide is tested
Two separate analyses are carried out on every lot before it is released, and both appear on the certificate. Identity is confirmed by LC-MS against the expected mass for the sequence. Purity is determined by RP-HPLC peak area.
For a peptide of this length the related substance profile carries more information than the purity figure alone. The certificate reports the chromatogram, and that is the part worth reading.
Purity specification for retatrutide
Lots are released against a ≥99% purity specification, determined by RP-HPLC peak area. The figure for the lot you receive is stated on its certificate of analysis and may differ from the specification.
A specification is a release threshold, not a description of every lot. Where a measured figure and the specification differ, the certificate is the record that applies to your material. Analytical figures relate to the lot they are published against and carry no implication of suitability for any purpose beyond laboratory research.
Research grade material is not manufactured under the controls that apply to a licensed medicinal product. A purity figure on a certificate of analysis is not a statement about fitness for any purpose other than laboratory research.
Storing retatrutide
Lyophilised material is shipped under cold chain and should be returned to freezer storage on arrival. Store the sealed vial dry at −20°C or below, protected from light and moisture.
Allow the vial to reach room temperature before breaking the seal, so that moisture does not condense onto the cake.
Preparing stock solutions
Prepare stock solutions in sterile water or an appropriate aqueous buffer for analytical work, at a concentration suited to your assay. Confirm solubility against the certificate of analysis before preparing stocks. Introduce solvent slowly against the vial wall rather than directly onto the cake, and allow the material to dissolve without agitation. Do not vortex.
Peptide solutions are less stable than lyophilised powder. Prepare close to the point of use, hold at 2–8°C for short periods only, and avoid repeated freeze and thaw cycles. Adsorption to plastic surfaces can reduce effective concentration in dilute working solutions, so use low binding consumables where the assay is sensitive to this.
Handling and disposal
Assess the hazards of this material before handling and use appropriate controls and protective equipment. It has not been characterised toxicologically for the purposes of this supply and should be treated as potentially hazardous.
Record the lot number from the vial label in your own inventory alongside the certificate of analysis, storage temperature and disposal route. Institutions holding investigational compounds should record them in the inventory that satisfies their own chemical hygiene plan, and should retain shipping documentation in line with their record keeping policy.
Dispose of unused material, vials and packaging lawfully and in line with your institution’s waste procedures. Do not dispose to drain.
Is retatrutide an approved medicine?
No. It holds no marketing authorisation from the MHRA, the FDA or the EMA, and it is not approved in any territory for any indication. It is an investigational compound in active clinical development. It may not lawfully be supplied for use in humans outside an authorised clinical trial.
Can I buy this for personal use?
No. Sale is restricted to persons aged 18 or over who are qualified researchers, or who purchase on behalf of a research institution, laboratory or business. This website is not an offer to supply to the general public, and this material is not supplied for use in humans or animals under any circumstances.
Why does this page not describe what the compound is being studied for?
Because describing an indication would describe a use that this material is not supplied for. This listing is an analytical reference standard. Investigators working on the pharmacology should go to the primary literature and the clinical trial registry record, which are the appropriate sources.
Is this the same as the material used in clinical trials?
No. Research grade material is not manufactured under the controls that apply to an investigational medicinal product supplied to a trial, and no comparison should be drawn between the two. The certificate of analysis describes the lot supplied and nothing beyond it.
What purity specification does this material meet?
Lots are released against a ≥99% specification, determined by RP-HPLC peak area. The figure for the lot you receive is stated on its certificate of analysis. For a peptide of this length the related substance profile on the chromatogram carries more information than the headline figure.
How do I match my vial to its certificate?
By lot number. The vial label carries the compound, the labelled quantity and the lot number, and the certificate is published against that same lot number.
Which labelled quantity do I receive?
The one selected at checkout. It is printed on the vial label and stated on the certificate of analysis.
How is it shipped?
In temperature stable, plainly labelled packaging on a tracked UK service. Compound names do not appear on the outer packaging.
Are prices shown with VAT?
Prices are shown in pounds sterling. Any VAT that applies is calculated and displayed at checkout, together with the delivery charge, before you confirm payment. The total shown at checkout is the total you pay.
Looking for something else?
Tell us the compound and quantity you are looking for and we will confirm availability and lead time. Research use only.
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