GHK-Cu 100mg
£35.00
Copper complex of the tripeptide glycyl-L-histidyl-L-lysine, supplied as a reference standard for laboratory research.
- Gly-His-Lys coordinated with copper(II)
- Lot matched certificate of analysis with every order
- Research use only. Not for human or veterinary use
17 in stock
- Research use only Not for human or veterinary use
- Certificate per lot Published against the lot number
- Independently tested RP-HPLC with LC-MS identity
- Restricted sale 18+ qualified researchers only
Certificates of analysis
Every lot is analysed by RP-HPLC with LC-MS identity confirmation. Select a lot to view its full report.
What is GHK-Cu?
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, supplied as a reference standard for laboratory research. It is used in metallopeptide and coordination chemistry work.
GHK-Cu structure and coordination
The peptide component is Gly-His-Lys. In the free peptide form it carries CAS 49557-75-7, molecular formula C14H24N6O4 and a molecular weight of 340.38 g/mol.
The copper is coordinated by the peptide rather than present as a separate salt, which is what makes this a complex rather than a mixture. The complex carries a characteristic blue colouration that distinguishes it visually from the uncomplexed peptide.
Why the complex figures are not published here
Public chemical records for the copper complex are not consistent with one another on formula, molecular weight and compound identifier. Rather than publish a figure that may contradict the material supplied, the formula and molecular weight of the complex are taken from the certificate of analysis for the lot.
Research use only
NH Peptides supplies GHK-Cu as an analytical reference standard for laboratory research. It is not a cosmetic, a cosmetic ingredient or a personal care product, it is not supplied for any use in humans or animals, and no information on this page describes or implies any such use.
Related material in the catalogue
GHK-Cu is the only metallopeptide complex currently held. It is handled differently from the plain peptides in the catalogue, both because the coordination chemistry is pH sensitive and because copper containing waste has its own disposal route.
Analysis and certification
Each lot of GHK-Cu is analysed by an independent laboratory before release. The certificate of analysis is published against the lot number rather than the product page, so the document you read is the document for the vial you receive.
Purity specification for GHK-Cu
Lots are released against a ≥99% purity specification, determined by RP-HPLC peak area. The figure for the lot you receive is stated on its certificate of analysis and may differ from the specification.
A specification is a release threshold, not a description of every lot. Where a measured figure and the specification differ, the certificate is the record that applies to your material. Analytical figures relate to the lot they are published against and carry no implication of suitability for any purpose beyond laboratory research.
| Compound | GHK-Cu |
|---|---|
| Also known as | Copper tripeptide-1 |
| Class | Metallopeptide complex |
| Peptide sequence | Gly-His-Lys |
| Metal | Copper(II) |
| Free peptide CAS | 49557-75-7 |
| Free peptide formula | C14H24N6O4 |
| Free peptide molecular weight | 340.38 g/mol |
| Complex formula | Stated on the certificate of analysis |
| Complex molecular weight | Stated on the certificate of analysis |
| Appearance | Blue lyophilised powder |
| Purity specification | ≥99% |
| Identity method | LC-MS |
| Purity method | RP-HPLC |
| Labelled quantity | 100mg |
Characterisation. Free peptide record: PubChem CID 73587. Public records for the copper complex are not consistent, so the formula and molecular weight of the complex are taken from the certificate of analysis for the lot supplied.
How GHK-Cu is tested
Two separate analyses are carried out on every lot before it is released, and both appear on the certificate.
RP-HPLC, for purity
Reversed phase high performance liquid chromatography separates the material by hydrophobicity. The main peak is integrated against the total peak area to give the purity figure. This is what the ≥99% specification refers to, and it is a measure of how much of the material is the intended compound rather than related substances, residual reagents or truncated sequences.
LC-MS, for identity
Liquid chromatography coupled to mass spectrometry confirms that the material eluting in the main peak has the expected mass. Purity alone does not establish identity: a lot can be 99% pure and still be the wrong compound. The two analyses answer different questions and both are needed.
What arrives with the order
- The vial, labelled with compound, labelled quantity and lot number
- A dispatch note listing the lot numbers supplied
- A storage and handling sheet
- The certificate of analysis for the lot, published against the lot number
If any of these is missing, or if the lot number on the vial does not match the certificate, contact us before using the material.
Storing GHK-Cu
Store the sealed vial dry at −20°C or below, protected from light and moisture. Return to freezer storage on arrival.
Preparing GHK-Cu solutions
Prepare solutions in sterile water or an appropriate aqueous buffer at a concentration suited to your assay, close to the point of use.
The copper complex is pH sensitive and can dissociate outside its stable range. Confirm buffer conditions against the certificate of analysis before preparing stocks, and be aware that dissociation will change what you are measuring before it is visible.
Handling and disposal of copper containing waste
Assess the hazards of this material before handling and use appropriate controls and protective equipment. Anyone handling it must be trained and competent to do so.
This is a copper containing compound. Dispose of unused material, vials and packaging in line with your institution’s procedures for metal containing waste, not as general laboratory waste.
On receipt
Check the parcel before putting the material away. Three things are worth two minutes:
- Packaging integrity. Confirm the vial is intact, the seal is unbroken and the insulated packaging has not failed in transit.
- Lot number. Check the number on the vial label against the certificate of analysis and against the dispatch note. All three should agree.
- Return to storage. Move the material into its stated storage conditions promptly rather than leaving it at ambient temperature.
If anything does not match, or the packaging has clearly failed, contact us before using the material. Problems visible on arrival should be reported within 7 days so a carrier claim remains possible.
Record keeping
Record the lot number in your notes at the point of first use, alongside the date the vial was opened and the concentration of any stock solution prepared. Certificates are published against the lot number rather than the product, so the lot number is the only reliable link between your results and the analytical data for the material that produced them.
That link matters later. If a question arises about a result months after the work, the lot number is what makes the material traceable and the work auditable.
What purity specification does this material meet?
Lots are released against a ≥99% specification. The figure for the lot you receive is stated on its certificate of analysis.
How do I match my vial to its certificate?
By lot number. The vial label carries the compound, the labelled quantity and the lot number, and the certificate is published against that same lot number.
Why is the powder blue?
The colour comes from the coordinated copper(II). It is a characteristic of the complex and is expected.
Is this a cosmetic ingredient?
No. Copper tripeptide-1 is a recognised cosmetic ingredient name, but this material is supplied as a laboratory reference standard only. It is not a cosmetic, cosmetic ingredient or personal care product and is not for human or animal use.
How should copper containing waste be handled?
In line with your institution’s procedures for metal containing waste. Do not dispose of it as general laboratory waste.
How is it shipped?
In temperature stable, plainly labelled packaging on a tracked UK service. Compound names do not appear on the outer packaging.
Who is eligible to order?
Sale is restricted to persons aged 18 or over who are qualified researchers, or who purchase on behalf of a research institution, laboratory or business. This website is not an offer to supply to the general public. Full details are in our research use only policy.
Are prices shown with VAT?
Prices are shown in pounds sterling. Any VAT that applies is calculated and displayed at checkout, together with the delivery charge, before you confirm payment. The total shown at checkout is the total you pay.
What happens if the lot changes between orders?
Each lot has its own certificate of analysis. If you reorder and a new lot is in stock, you receive that lot’s certificate. Record the lot number for each order separately rather than assuming continuity between them, since analytical figures are specific to the lot.
Can I order a quantity that is not listed?
Contact us with the compound and the quantity you need and we will confirm what is available. Availability depends on the lots currently held.
Do you provide dosing or protocol guidance?
No. We do not provide dosing information, administration guidance or protocol design, by any channel, and we cannot answer questions of that kind. Material is supplied for laboratory research only. Technical information we publish relates to identity, purity, storage and laboratory handling.
Looking for something else?
Tell us the compound and quantity you are looking for and we will confirm availability and lead time. Research use only.
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