Prostamax 20mg
£37.50
Synthetic tetrapeptide, supplied lyophilised as a reference standard for laboratory research.
- Defined sequence, produced by solid phase synthesis
- Lot matched certificate of analysis with every order
- Research use only. Not for human or veterinary use
24 in stock
- Research use only Not for human or veterinary use
- Certificate per lot Published against the lot number
- Independently tested RP-HPLC with LC-MS identity
- Restricted sale 18+ qualified researchers only
Certificates of analysis
Every lot is analysed by RP-HPLC with LC-MS identity confirmation. Select a lot to view its full report.
What is Prostamax
Prostamax is the trade name for the synthetic tetrapeptide KEDP, sequence Lys-Glu-Asp-Pro, supplied as a lyophilised powder for laboratory research. The material is produced by solid phase peptide synthesis as a single defined sequence and released against a lot specific certificate of analysis.
KEDP identity and structure
KEDP is a four residue sequence comprising lysine, glutamic acid, aspartic acid and proline. Short peptides are useful reference standards for analytical method development because they give simpler chromatograms and fewer variables to control than longer sequences.
Synthetic material, not a tissue extract
Short peptides of this class are also supplied elsewhere as fractions extracted from animal tissue. The two are not equivalent. An extract is a heterogeneous mixture that cannot be characterised by sequence, whereas a synthetic peptide can be confirmed by mass and by sequence analysis.
The material supplied here is synthetic and of the stated sequence, and that is confirmed on the certificate of analysis for the lot. Investigators reading the older extract literature should not assume that work transfers to this material, because the two were not characterised to the same standard.
Specification figures for the lot
The exact molecular formula, molecular weight, CAS reference and measured purity for the lot supplied are stated on its certificate of analysis. Published figures for research peptides are not always consistent between sources, so this page defers to the certificate rather than restating a value that may not match the material in the vial.
Working with tetrapeptides
Tetrapeptides behave differently from longer sequences in handling. They are generally more soluble and mass differences between related impurities are proportionally larger, which makes them easier to resolve by RP-HPLC. Sequences carrying both acidic and basic side chains, as KEDP does, are sensitive to buffer pH in solution, so confirm buffer compatibility before preparing stocks.
Analysis and certification
Each lot of KEDP is analysed by an independent laboratory using RP-HPLC with LC-MS identity confirmation before it is released for sale. The certificate of analysis is published against the lot number rather than the product page, so the document you read is the document for the vial you receive.
Research use only
NH Peptides supplies KEDP as an analytical reference standard for laboratory research. It is not supplied for any use in humans or animals, and no information on this page describes or implies any such use.
| Compound | KEDP Tetrapeptide (Prostamax) |
|---|---|
| Class | Synthetic tetrapeptide |
| Amino acids | 4 |
| Sequence | Lys-Glu-Asp-Pro (K-E-D-P) |
| CAS number | Stated on the lot certificate of analysis |
| Molecular formula | Stated on the lot certificate of analysis |
| Molecular weight | Stated on the lot certificate of analysis |
| Production method | Solid phase peptide synthesis |
| Origin | Synthetic. Not of animal tissue origin |
| Appearance | White to off white lyophilised powder |
| Purity specification | Stated on the lot certificate of analysis |
| Identity method | LC-MS |
| Purity method | RP-HPLC |
| Labelled quantity | 20 mg per vial |
| Presentation | Lyophilised, sealed glass vial |
| Intended use | Research use only. Not for human or veterinary use |
Storing the sealed vial
Lyophilised KEDP is shipped under cold chain and should be returned to freezer storage on arrival. Store the sealed vial dry at -20°C or below, protected from light and moisture. Under those conditions the lyophilised material is stable for the shelf life stated on the lot certificate of analysis.
Allow the sealed vial to reach room temperature before breaking the seal, so that atmospheric moisture does not condense onto the lyophilised cake. Avoid repeated opening and re-sealing of the vial for weighing, and do not decant powder between containers.
Preparing stock solutions
Prepare stock solutions in sterile water or an appropriate aqueous buffer for analytical work, at a concentration suited to your assay. Concentrations are expressed in milligrams per millilitre. Confirm buffer compatibility with a small trial volume before scaling to a working stock.
KEDP carries both acidic side chains (glutamic acid and aspartic acid) and a basic side chain (lysine), so solubility and stability are sensitive to buffer pH. Neutral to mildly acidic aqueous buffers are generally suitable for this class of short peptide, but the correct choice depends on the downstream method.
Reconstituted stability
Once reconstituted, treat stock solutions as short life material. Store aliquots at -20°C or lower, avoid repeated freeze thaw cycles, and validate the working timeframe against your own laboratory method. Working dilutions used at the bench are best prepared fresh on the day of use.
Handling and disposal
Handle the material in accordance with the general laboratory practice of your institution. Wear appropriate personal protective equipment, work in a suitable area, and dispose of vials, waste solutions and consumables through your organisation's laboratory waste stream in line with local regulations.
This material is supplied for laboratory research only. No dosing or administration guidance is provided.
Is Prostamax the same material as prostate tissue extract?
No. Prostamax is a synthetic tetrapeptide of defined sequence, produced by solid phase peptide synthesis. Tissue derived preparations are heterogeneous mixtures that cannot be characterised by a single sequence and are not equivalent to the synthetic material supplied here.
What sequence is supplied under the Prostamax label?
Prostamax is the tetrapeptide KEDP, comprising lysine, glutamic acid, aspartic acid and proline. The exact molecular formula, molecular weight and CAS reference for the lot supplied are stated on the lot certificate of analysis.
Why are the sequence and molecular figures not printed on this page?
The certificate of analysis is the primary specification document for the lot in your vial. Published figures for research peptides are not always consistent between sources, so this page defers to the certificate rather than restating a value that may not match the material shipped.
What solvent should I use to reconstitute KEDP?
Sterile water or an appropriate aqueous buffer is normally used for analytical work. Because KEDP carries both acidic and basic side chains, solubility and stability are sensitive to buffer pH, so confirm compatibility with a small trial volume before scaling to a working stock.
How stable are reconstituted stock solutions?
Treat reconstituted stocks as short life material. Store aliquots at -20°C or lower, avoid repeated freeze thaw cycles, and validate the working timeframe against your own laboratory method. Working dilutions are best prepared fresh on the day of use.
How should I confirm identity in my own laboratory?
The catalogue release method is RP-HPLC purity with LC-MS identity confirmation. Investigators wishing to repeat identity in house can run mass spectrometry against the sequence stated on the certificate of analysis for the lot.
How do I match my vial to its certificate of analysis?
Each vial carries a lot number on the label. The corresponding certificate is published against that lot number, so the document you read is the document for the vial you receive.
How is the material shipped?
Orders leave our High Wycombe facility in temperature stable, plainly labelled packaging on a tracked UK service. Please return the vial to freezer storage on arrival.
What happens if the lot changes between orders?
Analytical reference material is released lot by lot, and the certificate you receive corresponds to the vial in that shipment. Between orders the lot number may change, and the accompanying certificate will change with it.
Looking for something else?
Tell us the compound and quantity you are looking for and we will confirm availability and lead time. Research use only.
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