What is Ipamorelin?
Ipamorelin is a synthetic peptide that acts as a selective growth hormone secretagogue, supplied in research settings as a lyophilised powder. It is studied for its interaction with the ghrelin receptor (GHS-R1a) and its effects on growth hormone release pathways.
Ipamorelin structure
Ipamorelin is a pentapeptide comprising five amino acid residues. Its sequence distinguishes it from other synthetic growth hormone secretagogues and provides the basis for its identification as a separate research compound.
Specification figures for Ipamorelin
The amino acid sequence, molecular formula and molecular weight for the supplied lot are stated on its certificate of analysis. Published figures can vary between sources and product forms, so the certificate of analysis is the primary reference for the specific material supplied.
Regulatory status
Ipamorelin is not authorised as a medicine by the UK Medicines and Healthcare products Regulatory Agency (MHRA). Its regulatory status may vary by jurisdiction, and research-use supply should not be interpreted as authorisation for medical use. NH Peptides supplies this product solely as laboratory research material, not for human or veterinary use.
Analysis and certification
Each lot of Ipamorelin should be supported by appropriate analytical documentation. Where independent laboratory testing using reverse-phase high-performance liquid chromatography (RP-HPLC) and liquid chromatographyโmass spectrometry (LC-MS) has been performed, the results should be recorded on the corresponding certificate of analysis. Certificates should be linked to the relevant lot number so that the documentation can be matched to the material supplied.
Research use only
NH Peptides supplies Ipamorelin solely as a research reference material for laboratory investigation. It is not supplied for administration to humans or animals, and the information on this page does not describe or imply suitability for such use.
Purity specification for Ipamorelin
The purity specification for Ipamorelin should be stated in accordance with the supplier’s documented release criteria. Where a lot is specified at โฅ99% purity by RP-HPLC peak area, this should be supported by the relevant analytical documentation. The measured result for the supplied lot should be taken from its certificate of analysis.
A purity specification represents a stated release threshold and is not a guarantee that every lot has the same measured result. Where a measured value and the specification differ, the lot-specific certificate of analysis is the reference record for that material. Analytical results relate to the tested lot and do not imply suitability for any purpose beyond the stated laboratory research context.
| Compound | Ipamorelin |
|---|
| Class | Synthetic peptide, growth hormone secretagogue |
| Amino acids | 5 |
| Sequence | Stated on the certificate of analysis |
| CAS number | Stated on the certificate of analysis |
| Molecular formula | Stated on the certificate of analysis |
| Molecular weight | Stated on the certificate of analysis |
| Appearance | White to off-white lyophilised powder |
| Purity specification | โฅ99%, where supported by the applicable specification |
| Identity method | LC-MS, where documented |
| Purity method | RP-HPLC, where documented |
| Solubility | Refer to the applicable product and batch documentation |
| Labelled quantity | Per variation, stated on the vial label |
How Ipamorelin is tested
Where the testing has been performed, the certificate of analysis should document the analytical methods used for each lot before release.
RP-HPLC, for purity
Reversed-phase high-performance liquid chromatography (RP-HPLC) separates components of a sample according to their interactions with the chromatographic stationary phase and mobile phase. The relative area of the principal peak can be used to report chromatographic purity by peak-area percentage.
A stated โฅ99% specification represents a defined acceptance threshold when supported by the applicable release criteria. Peak-area purity is an analytical measurement and does not, by itself, establish absolute chemical purity or confirm the identity of the compound.
LC-MS, for identity
Liquid chromatography coupled with mass spectrometry (LC-MS) can support compound identification by separating sample components and measuring their mass-to-charge ratios. Results can be compared with the expected characteristics of Ipamorelin to support identity confirmation.
Purity and identity are separate analytical questions. A high chromatographic purity result alone does not establish that a sample is Ipamorelin; appropriate identity testing provides complementary evidence. The methods and results applicable to each lot should be recorded in its certificate of analysis.
What arrives with the order
- The vial, labelled with the compound name, labelled quantity and lot number
- A dispatch note listing the lot numbers supplied, where applicable
- A storage and handling sheet, where provided
- The certificate of analysis corresponding to the supplied lot, where available
If documentation is missing or the lot number on the vial does not match the certificate of analysis, contact NH Peptides for clarification before the material is used. The supplied documentation should be checked against the actual product and batch.
Storing Ipamorelin
Store Ipamorelin in accordance with the storage conditions specified by the manufacturer and the applicable certificate of analysis. Keep the vial sealed and protect the material from moisture and light. If refrigerated or frozen storage is specified, follow the documented temperature requirements and any applicable shipping instructions.
Preparing Ipamorelin stock solutions
For laboratory analytical work, preparation of Ipamorelin stock solutions should follow the validated procedure for the intended analytical method and the material's supporting documentation. Confirm the appropriate solvent, compatibility and concentration requirements before preparing a solution.
Peptide solutions may have different stability characteristics from lyophilised material. Solution stability depends on factors including solvent composition, temperature, concentration and storage duration. Use documented stability information where available, and avoid repeated freezeโthaw cycles where these may affect sample integrity.
Handling and disposal
Assess the hazards associated with Ipamorelin before handling and apply appropriate laboratory controls and protective equipment in accordance with your institution's risk assessment. Where toxicological information is incomplete, treat the material cautiously and avoid unnecessary exposure.
Dispose of unused material, vials and packaging in accordance with applicable waste regulations and your institution's procedures. Personnel handling the material should be appropriately trained and competent.
On receipt
Check the parcel and product documentation before placing the material into storage. Three checks are particularly important:
- Packaging integrity. Confirm that the vial is intact, the seal is undamaged and the packaging shows no evidence of damage or failure during transit.
- Lot number. Compare the number on the vial label with the certificate of analysis and dispatch documentation, where provided. The details should correspond to the same lot.
- Storage conditions. Check the stated storage requirements and place the material into the specified conditions promptly after receipt.
If any information does not match, or the packaging appears damaged, contact NH Peptides before using the material. Report visible delivery or packaging problems within 7 days of receipt so they can be assessed in line with the applicable delivery and claims procedures.
Record keeping
For laboratory traceability, record the Ipamorelin lot number alongside the date the material is received and, where relevant, the date the vial is opened. If analytical stock solutions are prepared, record the preparation details in accordance with your laboratory's procedures.
Certificates of analysis should be matched to the relevant lot rather than treated as generic documentation for every product unit. Keeping the lot number with your analytical records helps maintain traceability between the material tested and the associated analytical documentation.